Lasers for matrix‐assisted laser desorption ionization

نویسندگان

چکیده

Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry was introduced over 30 years ago, and it now plays a key role in several areas, including the characterization of microorganisms tissue imaging. Lasers are, course, central component MALDI spectrometers, but commercial systems, type is determined by instrument manufacturer, for operator, their only practical consideration selection optimal power, or fluence, that gives them best quality spectrum given sample matrix combination. In Special Feature this month, Dr. Kermit K. Murray, Department Chemistry, Louisiana State University, Baton Rouge, LA, provides detailed discussion its matrix-assisted desorption/ionization. Dr Murray's article includes brief history development use lasers ionization he describes wide range lasers, wavelengths configurations, dual-pulse have been developed evaluated during evolution spectrometry. For any spectrometrist using MS work, essential background reading on one most important, poorly understood components powerful analytical tool.

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ژورنال

عنوان ژورنال: Journal of Mass Spectrometry

سال: 2021

ISSN: ['1076-5174', '1096-9888']

DOI: https://doi.org/10.1002/jms.4557